There's nothing like seeing South Carolina on two wheels. Join us for the best-supported, most impactful cycling weekend of the summer!

Every July, cyclists take a three-day, scenic ride from the South Carolina foothills to the coast, all to raise funds and awareness for the research, care and support efforts of the Alzheimer's Association®. Virtual Challenge participants pedal their miles throughout July wherever and whenever they choose.

For 2025, we have two Group Ride options: The Grand Tour (257 miles) and The Half Tour (136 miles). The Half Tour will be the same amazing Ride to End ALZ South Carolina experience with a little less time on the road!

From the time you arrive, we take care of all of the details. All meals are provided, along with daily luggage and bus transportation plus discounted rates on nightly lodging. Rest Stops staffed by our enthusiastic volunteers offer hydration and snacks every 10-15 miles. SAG, mechanical and medical support is always available. And, once you’ve crossed the iconic Ravenel Bridge in Charleston and finished your remarkable three-day journey, we'll celebrate in a big way at the finish line!

Ride Schedule:

July 11-13, 2025

Pre-Event (Wednesday)

Pre-Ride Packet Pick-Up (Option 1)
11:00 AM - 2:00 PM
Alzheimer’s Association
123 W Antrim Dr, Greenville, SC 29607

Pre-Event (Thursday)

Buses to Simpsonville (*by reservation)
1:00 PM: Loading begins
2:00 PM: Buses depart
Hampton Inn Patriots Point
255 Sessions Way, Mt. Pleasant, SC 29464

Pre-Ride Packet Pick-Up (Option 2)
11:00 AM - 7:00 PM
The Mill at Fountain Inn
100 Ellison St., Fountain Inn, SC 29644

Lodging

Hampton Inn Simpsonville
3934 Grandview Dr., Simpsonville, SC 29680

Holiday Inn Express
642 Fairview Rd., Simpsonville, SC 29680

Day 1 (Friday)

Opening Ceremony and Start

7:00 AM: Packet Pick-Up Opens
8:00 AM: Ride Starts
Heritage Park
861 SE Main St., Simpsonville, SC 29681

Lodging:

Newberry College
2100 College St., Newberry, SC 29108
*Friday Finish & Dinner; Saturday Start

Holiday Inn Newberry
121 Truman Ave., Newberry, SC 29108

Hampton Inn Newberry
1201 Nance St., Newberry, SC 29108

Home2 Suites
111 Landworks Ave., Newberry, SC 29108

Dinner
6:00 PM
Newberry College
2100 College St., Newberry, SC 29108

Day 2 (Saturday)

7:00 AM Ride Start - Newberry College

Lodging:

SPARK by Hilton (former Country Inn)
731 Citadel Rd., Orangeburg, SC 29118
*Saturday Finish; Sunday Start

Comfort Inn & Suites
746 Citadel Rd., Orangeburg, SC 29118

Hampton Inn Orangeburg
749 Citadel Rd., Orangeburg, SC 29118

Tru by Hilton
739 Citadel Rd., Orangeburg, SC 29118

Dinner
6:00 PM
First Baptist Church Family Life Center
2875 Columbia Rd NE, Orangeburg, SC 29118

Day 3 (Sunday)

7:00 AM Ride Start - SPARK by Hilton

Lodging

Hampton Inn Patriots Point
255 Sessions Way, Mt. Pleasant, SC 29464

Springhill Suites
245 Magrath Darby Blvd., Mt. Pleasant, SC 29464
Bus to Simpsonville (*by reservation)

4:45 PM - Loading begins. 5:30 PM - Bus departs
Mount Pleasant Memorial Waterfront Park
99 Harry M. Hallman Jr Blvd, Mt Pleasant, SC 29464
Dinner Shuttle Service (On Your Own)

6:15 PM
Departing from Hampton Inn to Shem Creek Restaurant District

Post-Event (Monday)

Buses to Simpsonville (*by reservation)

8:00 AM - Loading begins. 9:00 AM - Buses depart. Hampton
Inn Patriots Point
255 Sessions Way, Mt. Pleasant, SC

Spring Hill Suites
245 Magrath Darby Blvd., Mt Pleasant, SC 29464

Click here to Register.